4LI0

Crystal structure of GDP-bound Rab8:GRAB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ras-related protein Rab-8A	polymer	186	21259.4	2	UniProt (P61006) Pfam (PF00071) In PDB	Homo sapiens (human)	Oncogene c-mel
2	C, D, E, F	Guanine nucleotide exchange factor for Rab-3A	polymer	84	9800.1	4	UniProt (Q8TBN0) Pfam (PF06428) In PDB	Homo sapiens (human)	Rab-3A-interacting-like protein 1, Rab3A-interacting-like protein 1, Rabin3-like 1
3	A, B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)

Sequence modifications

A, B: 1 - 184 (UniProt: P61006)

PDB	External Database	Details
Gly -1	-	expression tag
His 0	-	expression tag

C, D, E, F: 73 - 154 (UniProt: Q8TBN0)

PDB	External Database	Details
Gly 71	-	expression tag
Pro 72	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	81719.3
Non-Polymers*	Number of molecules	2
	Total formula weight	886.4
All*	Total formula weight	82605.7

*Water molecules are not included.