4LHW
Crystal structure of Rab8 in its active GppNHp-bound form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Ras-related protein Rab-8A | polymer | 174 | 19967.9 | 5 | UniProt (P61006) Pfam (PF00071) | Homo sapiens (human) | Oncogene c-mel |
| 2 | F, I, K, M, O (A, B, C, D, E) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 3 | G, J, L, N, P (A, B, C, D, E) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 5 | Chemie (GNP) | |||
| 4 | H (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | Q, R, S, T, U (A, B, C, D, E) | water | water | 18.0 | 1049 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 6 - 176 (UniProt: P61006)
| PDB | External Database | Details |
|---|---|---|
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 99839.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2850.7 | |
| All* | Total formula weight | 102690.3 |
