4LHU

Crystal Structure of 9C2 TCR bound to CD1d

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Antigen-presenting glycoprotein CD1d	polymer	278	31758.8	1	UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (human)	R3G1
2	B	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)
3	D	9C2 TCR delta chain	polymer	236	26265.9	1	Pfam (PF07686) Pfam (PF07654) UniProt (by SIFTS) (Q6PJ56) In PDB	Homo sapiens (human)
4	G	9C2 TCR gamma chain	polymer	251	28676.5	1	Pfam (PF07654) UniProt (by SIFTS) (P0CF51) In PDB	Homo sapiens (human)
5	C, E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
6	F	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
8	A	beta-D-mannopyranose	non-polymer		180.2	1	Chemie (BMA)
9	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
10	A	(15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide	non-polymer		828.3	1	Chemie (JLS)
11	G	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
12		water	water		18.0	109	Chemie (HOH)

Sequence modifications

A: 6 - 277 (UniProt: P15813)

PDB	External Database	Details
His 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	98580.5
Branched	Number of molecules	3
	Total formula weight	1435.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1289.4
All*	Total formula weight	101305.2

*Water molecules are not included.