4LH0
Structure of mouse 1-Pyrroline-5-Carboxylate Dehydrogenase (ALDH4A1) complexed with glyoxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | polymer | 563 | 61954.2 | 2 | UniProt (Q8CHT0) Pfam (PF00171) | Mus musculus (mouse) | P5C dehydrogenase, Aldehyde dehydrogenase family 4 member A1 |
| 2 | C, E, F (A, B) | GLYOXYLIC ACID | non-polymer | 74.0 | 3 | Chemie (GLV) | |||
| 3 | D, G (A, B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 742 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 563 (UniProt: Q8CHT0)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Val 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Arg 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| His 20 | - | expression tag |
| Met 21 | - | expression tag |
| Ala 33 | Thr 32 | conflict |
| Thr 61 | Met 60 | conflict |
| Lys 468 | Gln 467 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 123908.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 698.7 | |
| All* | Total formula weight | 124607.1 |
