4LG9

Crystal structure of TBL1XR1 WD40 repeats

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	F-box-like/WD repeat-containing protein TBL1XR1	polymer	400	43649.5	1	UniProt (Q9BZK7) Pfam (PF00400)	Homo sapiens (human)	Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1
2	B, C, D, E, F... (A)	UNKNOWN ATOM OR ION	non-polymer			23	Chemie (UNX)
3	Y (A)	water	water		18.0	160	Chemie (HOH)

Sequence modifications

A: 134 - 514 (UniProt: Q9BZK7)

PDB	External Database	Details
Met 115	-	expression tag
Gly 116	-	expression tag
Ser 117	-	expression tag
Ser 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag
Ser 125	-	expression tag
Ser 126	-	expression tag
Gly 127	-	expression tag
Leu 128	-	expression tag
Val 129	-	expression tag
Pro 130	-	expression tag
Arg 131	-	expression tag
Gly 132	-	expression tag
Ser 133	-	expression tag
Met 438	Leu 438	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43649.5
Non-Polymers*	Number of molecules	23
	Total formula weight	0.0
All*	Total formula weight	43649.5

*Water molecules are not included.