4LG2

Crystal structure of Reston Ebola virus VP35 RNA binding domain bound to 12-bp dsRNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polymerase cofactor	polymer	146	16564.1	4	UniProt (Q8JPY0) Pfam (PF02097)	Reston ebolavirus (REBOV)
2	E, F, G, H (E, F, J, I)	dsRNA	polymer	12	3812.3	4
3	I, J, K, L (A, B, C, J)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B, C, D: 205 - 329 (UniProt: Q8JPY0)

PDB	External Database	Details
Met 184	-	expression tag
Ala 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag
Val 192	-	expression tag
Asp 193	-	expression tag
Asp 194	-	expression tag
Asp 195	-	expression tag
Asp 196	-	expression tag
Lys 197	-	expression tag
Glu 198	-	expression tag
Asn 199	-	expression tag
Leu 200	-	expression tag
Tyr 201	-	expression tag
Phe 202	-	expression tag
Gln 203	-	expression tag
Ser 204	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	81505.7
All*	Total formula weight	81505.7

*Water molecules are not included.