4LD2

Crystal structure of NE0047 in complex with cytidine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cytidine and deoxycytidylate deaminase zinc-binding region	polymer	197	20586.5	2	UniProt (Q82Y41) Pfam (PF00383)	Nitrosomonas europaea
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D (A)	4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE	non-polymer		243.2	1	Chemie (CTN) PubChem (16760387) PubChem (6175) PubChem (6253) PubChem (114682) PubChem (122948) PubChem (160696) PubChem (24729357) PubChem (25085165) PubChem (3013211) PubChem (44264135) PubChem (44307610) PubChem (44356841) PubChem (45109772) PubChem (453552) PubChem (638040) PubChem (1265901) PubChem (57764456) PubChem (57807005) PubChem (58460874) PubChem (58519508) PubChem (71230474) PubChem (59476533) PubChem (59713247) PubChem (54353063) PubChem (60138999) PubChem (66800112) PubChem (58899188) PubChem (68199635) PubChem (5702244) PubChem (596) PubChem (6476646) PubChem (6479885) PubChem (6551012) PubChem (6603781) PubChem (89495334) PubChem (6713582) PubChem (90089493) PubChem (70994952) PubChem (12358851) PubChem (6480064) PubChem (117732781) PubChem (122468509) PubChem (142117909) PubChem (148710634) PubChem (168266058) PubChem (171699434)
4	F, G (B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	H, I (A, B)	water	water		18.0	227	Chemie (HOH)

Sequence modifications

A, B: 1 - 193 (UniProt: Q82Y41)

PDB	External Database	Details
Gly -1	-	expression tag
His 0	-	expression tag
Gly 194	-	expression tag
Ser 195	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41172.9
Non-Polymers*	Number of molecules	5
	Total formula weight	498.2
All*	Total formula weight	41671.1

*Water molecules are not included.