4LAX
Crystal Structure Analysis of FKBP52, Complex with FK506
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase FKBP4 | polymer | 269 | 30671.6 | 1 | UniProt (Q02790) Pfam (PF00254) In PDB | Homo sapiens (human) | PPIase FKBP4, 52 kDa FK506-binding protein, 52 kDa FKBP, FKBP-52, 59 kDa immunophilin, p59, FK506-binding protein 4, FKBP-4, FKBP59, HSP-binding immunophilin, HBI, Immunophilin FKBP52, Rotamase |
2 | A | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 1 | Chemie (FK5) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A: 16 - 260 (UniProt: Q02790)
PDB | External Database | Details |
---|---|---|
Met -8 | - | expression tag |
Ser -7 | - | expression tag |
Tyr -6 | - | expression tag |
Tyr -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Asp 2 | - | expression tag |
Tyr 3 | - | expression tag |
Asp 4 | - | expression tag |
Ile 5 | - | expression tag |
Pro 6 | - | expression tag |
Thr 7 | - | expression tag |
Thr 8 | - | expression tag |
Glu 9 | - | expression tag |
Asn 10 | - | expression tag |
Leu 11 | - | expression tag |
Tyr 12 | - | expression tag |
Phe 13 | - | expression tag |
Gln 14 | - | expression tag |
Gly 15 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 30671.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1130.5 | |
All* | Total formula weight | 31802.1 |