4LAJ
Crystal structure of HIV-1 YU2 envelope gp120 glycoprotein in complex with CD4-mimetic miniprotein, M48U1, and llama single-domain, broadly neutralizing, co-receptor binding site antibody, JM4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (J, F, A, B) | HIV-1 YU2 gp120 envelope glycoprotein | polymer | 376 | 41695.4 | 4 | Pfam (PF00516) UniProt (by SIFTS) (P35961) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | E, F, G, H (K, D, G, C) | CD4-mimetic miniprotein M48U1 | polymer | 28 | 3056.8 | 4 | BIRD (PRD_001094) | ||
| 3 | I, J, K, L (H, M, L, I) | Llama single domain antibody, JM4 | polymer | 129 | 14010.5 | 4 | Pfam (PF07686) UniProt (by SIFTS) (A2KD57) | Lama glama (llama) | |
| 4 | AA, BA, CA, DA, EA... (F, A, J, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 35 | Chemie (NAG) | |||
| 5 | AB, BB, OA, PA, QA... (B, A, J) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 6 | CB (B) | 6-AMINOHEXANOIC ACID | non-polymer | 131.2 | 1 | Chemie (ACA) | |||
| 7 | DB, EB, FB, GB, HB... (J, F, A, B, K...) | water | water | 18.0 | 570 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 235050.9 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 8307.9 | |
| All* | Total formula weight | 243358.8 |
