4LAJ

Crystal structure of HIV-1 YU2 envelope gp120 glycoprotein in complex with CD4-mimetic miniprotein, M48U1, and llama single-domain, broadly neutralizing, co-receptor binding site antibody, JM4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
B	0019031	cellular_component	viral envelope
F	0019031	cellular_component	viral envelope
H	0002250	biological_process	adaptive immune response
H	0002376	biological_process	immune system process
H	0005576	cellular_component	extracellular region
H	0019814	cellular_component	immunoglobulin complex
I	0002250	biological_process	adaptive immune response
I	0002376	biological_process	immune system process
I	0005576	cellular_component	extracellular region
I	0019814	cellular_component	immunoglobulin complex
J	0019031	cellular_component	viral envelope
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0019814	cellular_component	immunoglobulin complex
M	0002250	biological_process	adaptive immune response
M	0002376	biological_process	immune system process
M	0005576	cellular_component	extracellular region
M	0019814	cellular_component	immunoglobulin complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Region: {"description":"CD4-binding loop","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Region: {"description":"V5","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	64
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	25
Details	Region: {"description":"V4","evidences":[{"source":"HAMAP-Rule","id":"MF_04083","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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