4L58
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase MLL5 | polymer | 69 | 8186.5 | 1 | UniProt (Q8IZD2) Pfam (PF20826) In PDB | Homo sapiens (human) | Lysine N-methyltransferase 2E, KMT2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5 |
| 2 | B | Histone H3 peptide | polymer | 12 | 1350.6 | 1 | UniProt (by SIFTS) (P84243) In PDB | Homo sapiens | H3K4me3 peptide |
| 3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 1 - 65 (UniProt: Q8IZD2)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | EXPRESSION TAG |
| Ser -2 | - | EXPRESSION TAG |
| His -1 | - | EXPRESSION TAG |
| Met 0 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9537.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 9667.9 |
