4L58
Crystal structure of the MLL5 PHD finger in complex with H3K4me3
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 101 |
| Chain | Residue |
| A | CYS19 |
| A | CYS22 |
| A | CYS44 |
| A | CYS47 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 102 |
| Chain | Residue |
| A | CYS5 |
| A | CYS7 |
| A | HIS27 |
| A | CYS30 |
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 43 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. Ci.Cgfthddgym....................................IcCdk..Csvw.QHidCmgidrqhipdt..................................YlCerC |
| Chain | Residue | Details |
| A | CYS5-CYS47 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | Zinc finger: {"description":"PHD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23798402","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24130829","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2LV9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4L58","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
