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4L4Z

Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transcriptional regulator LsrRpolymer26627924.12UniProt (P76141)
Pfam (PF04198)
Escherichia coli
2C, D
(A, B)
(2S)-2,3,3-trihydroxy-4-oxopentyl dihydrogen phosphatenon-polymer230.12Chemie (D5X)
3E, F
(A, B)
waterwater18.0173Chemie (HOH)
Sequence modifications
A, B: 53 - 317 (UniProt: P76141)
PDBExternal DatabaseDetails
Ser 52-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight55848.3
Non-Polymers*Number of molecules2
Total formula weight460.2
All*Total formula weight56308.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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