4L4T
Structure of human MAIT TCR in complex with human MR1-6-FP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein, Class I histocompatibility antigen-like protein |
| 2 | B, F (B, F) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | Beta-2-microglobulin form pI 5.3 |
| 3 | D, G (D, G) | MAIT T-cell receptor alpha chain | polymer | 203 | 22650.1 | 2 | Homo sapiens (human) | ||
| 4 | E, H (E, H) | MAIT T-cell receptor beta chain | polymer | 245 | 27546.6 | 2 | Pfam (PF07654) UniProt (by SIFTS) (P01850) | Homo sapiens (human) | |
| 5 | I, J (A, C) | 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde | non-polymer | 191.1 | 2 | Chemie (6FP) | |||
| 6 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 1293 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
| Ser 261 | Cys 283 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 187312.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 382.3 | |
| All* | Total formula weight | 187695.2 |
