4L17
GluA2-L483Y-A665C ligand-binding domain in complex with the antagonist DNQX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, E, G) | Glutamate receptor 2 | polymer | 263 | 29303.8 | 4 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
| 2 | E, G, I, K (A, C, E, G) | 6,7-DINITROQUINOXALINE-2,3-DIONE | non-polymer | 250.1 | 4 | Chemie (DNQ) | |||
| 3 | F, H, J (A, C, E) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | L, M, N, O (A, C, E, G) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 3 - 117 (UniProt: P19491)
A, C, E, G: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Tyr 94 | Leu 504 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Cys 153 | Ala 686 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117215.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1288.7 | |
| All* | Total formula weight | 118503.8 |
