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4KZ8

Crystal structure of AmpC beta-lactamase in complex with fragment 20 (1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Beta-lactamasepolymer35839587.92UniProt (P00811)
Pfam (PF00144)
Escherichia coliAmpC beta-lactamase, Cephalosporinase
2C, D, F, G
(A, B)
1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dionenon-polymer200.34Chemie (1U6)
3E
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
4H, I
(A, B)
waterwater18.0410Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79175.8
Non-Polymers*Number of molecules5
Total formula weight896.0
All*Total formula weight80071.8
*Water molecules are not included.

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PDB entries from 2025-12-24

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