4KVM
The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | N-terminal acetyltransferase A complex subunit nat1 | polymer | 734 | 84154.8 | 4 | UniProt (O74985) Pfam (PF12569) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | NatA complex subunit nat1 |
| 2 | E, F, G, H (E, F, G, H) | N-terminal acetyltransferase A complex catalytic subunit ard1 | polymer | 156 | 18030.8 | 4 | UniProt (Q9UTI3) Pfam (PF00583) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | NatA complex subunit ARD1 |
| 3 | I, J, K, L (I, J, K, L) | bisubstrate analog inhibitor | polymer | 4 | 392.4 | 4 | synthetic construct | ||
| 4 | AB, BA, BB, CA, CB... (C, B, D, A, E...) | CHLORIDE ION | non-polymer | 35.5 | 64 | Chemie (CL) | |||
| 5 | AA, TB (A, D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | AC, BC, CC, DC (I, J, K, L) | [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | non-polymer | 821.5 | 4 | Chemie (1XE) | |||
| 7 | EC, FC, GC, HC, IC... (A, B, C, D, E...) | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 729 (UniProt: O74985)
| PDB | External Database | Details |
|---|---|---|
| Ala 730 | - | expression tag |
| Ala 731 | - | expression tag |
| Ala 732 | - | expression tag |
| Ala 733 | - | expression tag |
| Ala 734 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 410311.7 | |
| Non-Polymers* | Number of molecules | 70 |
| Total formula weight | 5747.3 | |
| All* | Total formula weight | 416059.0 |
