4KVM
The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | N-terminal acetyltransferase A complex subunit nat1 | polymer | 734 | 84154.8 | 4 | UniProt (O74985) Pfam (PF12569) In PDB | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | NatA complex subunit nat1 |
2 | E, F, G, H | N-terminal acetyltransferase A complex catalytic subunit ard1 | polymer | 156 | 18030.8 | 4 | UniProt (Q9UTI3) Pfam (PF00583) In PDB | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | NatA complex subunit ARD1 |
3 | I, J, K, L | bisubstrate analog inhibitor | polymer | 4 | 392.4 | 4 | synthetic construct | ||
4 | C, B, D, A, E... | CHLORIDE ION | non-polymer | 35.5 | 64 | Chemie (CL) | |||
5 | A, D | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | I, J, K, L | [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | non-polymer | 821.5 | 4 | Chemie (1XE) | |||
7 | water | water | 18.0 | 325 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 729 (UniProt: O74985)
PDB | External Database | Details |
---|---|---|
Ala 730 | - | expression tag |
Ala 731 | - | expression tag |
Ala 732 | - | expression tag |
Ala 733 | - | expression tag |
Ala 734 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 410311.7 | |
Non-Polymers* | Number of molecules | 70 |
Total formula weight | 5747.3 | |
All* | Total formula weight | 416059.0 |