4KQM
Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Gsy2p | polymer | 724 | 82232.0 | 4 | UniProt (E7NKU1) Pfam (PF05693) UniProt (by SIFTS) (P27472) | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | E, H, M, P (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 3 | F, I, N, Q (A, B, C, D) | 6-O-phosphono-alpha-D-glucopyranose | non-polymer | 260.1 | 4 | Chemie (G6P) | |||
| 4 | G, J, O, R (A, B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) PubChem (8117) | |||
| 5 | K (C) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 6 | L (C) | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) |
Sequence modifications
A, B, C, D: 1 - 705 (UniProt: E7NKU1)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gln 169 | Glu 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 328927.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3442.0 | |
| All* | Total formula weight | 332369.9 |
