4KQM
Crystal structure of yeast glycogen synthase E169Q mutant in complex with glucose and UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Gsy2p | polymer | 724 | 82232.0 | 4 | UniProt (E7NKU1) Pfam (PF05693) UniProt (by SIFTS) (P27472) | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | E, H, M, P (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
| 3 | F, I, N, Q (A, B, C, D) | 6-O-phosphono-alpha-D-glucopyranose | non-polymer | 260.1 | 4 | Chemie (G6P) | |||
| 4 | G, J, O, R (A, B, C, D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 5 | K (C) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 6 | L (C) | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) |
Sequence modifications
A, B, C, D: 1 - 705 (UniProt: E7NKU1)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gln 169 | Glu 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 328927.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3442.0 | |
| All* | Total formula weight | 332369.9 |
