4KP4

Deciphering cis-trans directionality and visualizing autophosphorylation in histidine kinases.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Osmolarity sensor protein EnvZ, Histidine kinase	polymer	236	25850.3	2	UniProt (P0AEJ4) UniProt (Q9WZV7) Pfam (PF00512) Pfam (PF02518)	Escherichia coli	Sensor histidine kinase
2	C (A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
3	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	E, G, H (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5	F (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	I, J (A, B)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 223 - 253 (UniProt: P0AEJ4)
A, B: 271 - 290 (UniProt: Q9WZV7)
A, B: 1266 - 1450 (UniProt: P0AEJ4)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	51700.6
Non-Polymers*	Number of molecules	6
	Total formula weight	924.8
All*	Total formula weight	52625.4

*Water molecules are not included.