4KP4
Deciphering cis-trans directionality and visualizing autophosphorylation in histidine kinases.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ANP A 1501 |
| Chain | Residue |
| A | HIS243 |
| A | ALA1396 |
| A | GLY1401 |
| A | THR1402 |
| A | GLY1403 |
| A | LEU1404 |
| A | GLY1405 |
| A | LEU1406 |
| A | LEU1430 |
| A | MG1502 |
| A | ASN1347 |
| A | ARG1350 |
| A | TYR1351 |
| A | ASP1373 |
| A | GLY1377 |
| A | ILE1378 |
| A | ARG1392 |
| A | GLY1393 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1502 |
| Chain | Residue |
| A | ASN1347 |
| A | ARG1350 |
| A | ANP1501 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1503 |
| Chain | Residue |
| A | ARG1383 |
| A | GLY1423 |
| A | THR1424 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1501 |
| Chain | Residue |
| A | ARG1366 |
| A | MET1419 |
| B | GLY1326 |
| B | SER1327 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1502 |
| Chain | Residue |
| B | ARG1350 |
| B | ILE1399 |
| B | SER1400 |
| B | GLY1401 |
| B | THR1402 |
| B | HOH1602 |
| B | HOH1603 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4KP4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphohistidine; by autocatalysis","evidences":[{"source":"PROSITE-ProRule","id":"PRU00107","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8132603","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
