4KNN
Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Carbonic anhydrase 13 | polymer | 263 | 29613.3 | 2 | UniProt (Q8N1Q1) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase XIII, Carbonic anhydrase XIII, CA-XIII |
| 2 | C, K (B, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, L (B, A) | 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide | non-polymer | 343.8 | 2 | Chemie (E1F) | |||
| 4 | E, M (B, A) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 5 | F, G, O (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 6 | H, I, J (B) | ACETIC ACID | non-polymer | 60.1 | 3 | Chemie (ACY) | |||
| 7 | N (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | P, Q (B, A) | water | water | 18.0 | 568 | Chemie (HOH) |
Sequence modifications
B, A: 2 - 263 (UniProt: Q8N1Q1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59226.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1675.2 | |
| All* | Total formula weight | 60901.8 |
