4KNB
C-Met in complex with OSI ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Hepatocyte growth factor receptor | polymer | 287 | 32549.9 | 4 | UniProt (P08581) Pfam (PF07714) | Homo sapiens (human) | HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met |
| 2 | E, H, J, K (A, B, C, D) | 7-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[3,2-c]pyridin-6-amine | non-polymer | 490.4 | 4 | Chemie (1RU) | |||
| 3 | F, G, I (A, B) | GAMMA-BUTYROLACTONE | non-polymer | 86.1 | 3 | Chemie (GBL) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130199.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2219.7 | |
| All* | Total formula weight | 132419.1 |
