4KN6
Crystal structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with 6-fluoro-3-hydroxy-2-pyrazinecarboxamide (T-705) ribose-5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxanthine-guanine phosphoribosyltransferase | polymer | 216 | 24410.1 | 1 | UniProt (P00492) Pfam (PF00156) | Homo sapiens (human) | HGPRT, HGPRTase |
| 2 | B (A) | 6-fluoro-3-oxo-4-(5-O-phosphono-beta-D-ribofuranosyl)-3,4-dihydropyrazine-2-carboxamide | non-polymer | 369.2 | 1 | Chemie (1RP) PubChem (22662779) PubChem (60126677) PubChem (69875991) PubChem (70148580) PubChem (171391256) PubChem (171702772) | |||
| 3 | C (A) | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24410.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 369.2 | |
| All* | Total formula weight | 24779.3 |
