4KIK
Human IkB kinase beta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inhibitor of nuclear factor kappa-B kinase subunit beta | polymer | 677 | 78251.5 | 1 | UniProt (O14920) Pfam (PF00069) Pfam (PF18397) | Homo sapiens (human) | I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB |
| 2 | B (B) | Inhibitor of nuclear factor kappa-B kinase subunit beta | polymer | 677 | 78331.5 | 1 | UniProt (O14920) Pfam (PF00069) Pfam (PF18397) | Homo sapiens (human) | I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB |
| 3 | C, D (A, B) | K-252A | non-polymer | 467.5 | 2 | Chemie (KSA) PubChem (3813) PubChem (24867866) PubChem (3035817) PubChem (490561) PubChem (49868185) PubChem (127357) PubChem (6610352) PubChem (9890741) PubChem (9912410) PubChem (9912412) PubChem (9912413) PubChem (11612445) PubChem (98053103) PubChem (98118654) PubChem (101713437) PubChem (102446520) PubChem (162981511) PubChem (144411107) PubChem (162981512) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 2 - 664 (UniProt: O14920)
B: 2 - 664 (UniProt: O14920)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Ser 665 | - | expression tag |
| Pro 666 | - | expression tag |
| Gly 667 | - | expression tag |
| Arg 668 | - | expression tag |
| Pro 669 | - | expression tag |
| Leu 670 | - | expression tag |
| Asn 671 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Ser 665 | - | expression tag |
| Pro 666 | - | expression tag |
| Gly 667 | - | expression tag |
| Arg 668 | - | expression tag |
| Pro 669 | - | expression tag |
| Leu 670 | - | expression tag |
| Asn 671 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 156583.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 934.9 | |
| All* | Total formula weight | 157518.0 |
