4KIK

Human IkB kinase beta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Inhibitor of nuclear factor kappa-B kinase subunit beta	polymer	677	78251.5	1	UniProt (O14920) Pfam (PF00069) Pfam (PF18397)	Homo sapiens (human)	I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB
2	B (B)	Inhibitor of nuclear factor kappa-B kinase subunit beta	polymer	677	78331.5	1	UniProt (O14920) Pfam (PF00069) Pfam (PF18397)	Homo sapiens (human)	I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB, I-kappa-B kinase 2, IKK2, Nuclear factor NF-kappa-B inhibitor kinase beta, NFKBIKB
3	C, D (A, B)	K-252A	non-polymer		467.5	2	Chemie (KSA)
4	E, F (A, B)	water	water		18.0	221	Chemie (HOH)

Sequence modifications

A: 2 - 664 (UniProt: O14920)

PDB	External Database	Details
Met -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ser 665	-	expression tag
Pro 666	-	expression tag
Gly 667	-	expression tag
Arg 668	-	expression tag
Pro 669	-	expression tag
Leu 670	-	expression tag
Asn 671	-	expression tag

B: 2 - 664 (UniProt: O14920)

PDB	External Database	Details
Met -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ser 665	-	expression tag
Pro 666	-	expression tag
Gly 667	-	expression tag
Arg 668	-	expression tag
Pro 669	-	expression tag
Leu 670	-	expression tag
Asn 671	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	156583.1
Non-Polymers*	Number of molecules	2
	Total formula weight	934.9
All*	Total formula weight	157518.0

*Water molecules are not included.