4KIC
Crystal structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-methionine and phenylpyruvic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Methyltransferase MppJ | polymer | 357 | 39400.3 | 2 | UniProt (Q643C8) | Streptomyces hygroscopicus | |
| 2 | C, O (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | D, P (A, B) | 3-PHENYLPYRUVIC ACID | non-polymer | 164.2 | 2 | Chemie (PPY) PubChem (997) | |||
| 4 | E, Q (A, B) | FE (III) ION | non-polymer | 55.8 | 2 | Chemie (FE) PubChem (29936) | |||
| 5 | F, R (A, B) | (2R)-2-hydroxy-3-phenylpropanoic acid | non-polymer | 166.2 | 2 | Chemie (HF2) | |||
| 6 | G, H, I, J, K... (A, B) | CALCIUM ION | non-polymer | 40.1 | 13 | Chemie (CA) PubChem (271) | |||
| 7 | N (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) PubChem (30165) | |||
| 8 | Y, Z (A, B) | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 337 (UniProt: Q643C8)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 78800.6 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2217.1 | |
| All* | Total formula weight | 81017.7 |
