4KBQ
Structure of the CHIP-TPR domain in complex with the Hsc70 Lid-Tail domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase CHIP | polymer | 139 | 15884.1 | 2 | UniProt (Q9UNE7) Pfam (PF12895) | Homo sapiens (human) | Antigen NY-CO-7, CLL-associated antigen KW-8, Carboxy terminus of Hsp70-interacting protein, STIP1 homology and U box-containing protein 1 |
| 2 | C, D (D, C) | Heat shock cognate 71 kDa protein | polymer | 101 | 11423.7 | 2 | UniProt (P11142) | Homo sapiens (human) | Heat shock 70 kDa protein 8 |
| 3 | E, F, G, H (A, B, D, C) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 154 (UniProt: Q9UNE7)
D, C: 541 - 646 (UniProt: P11142)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Met 18 | - | expression tag |
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 533 | - | expression tag |
| Ile 534 | - | expression tag |
| Asp 535 | - | expression tag |
| Pro 536 | - | expression tag |
| Phe 537 | - | expression tag |
| Thr 538 | - | expression tag |
| Glu 539 | - | expression tag |
| Phe 540 | - | expression tag |
| - | Pro 626 | deletion |
| - | Gly 627 | deletion |
| - | Gly 628 | deletion |
| - | Gly 629 | deletion |
| - | Ala 630 | deletion |
| - | Pro 631 | deletion |
| - | Pro 632 | deletion |
| - | Ser 633 | deletion |
| - | Gly 634 | deletion |
| - | Gly 635 | deletion |
| - | Ala 636 | deletion |
| - | Ser 637 | deletion |
| - | Ser 638 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54615.6 | |
| All* | Total formula weight | 54615.6 |
