4K9Y
FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-urea
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Focal adhesion kinase 1 | polymer | 279 | 31957.9 | 1 | UniProt (Q05397) Pfam (PF07714) In PDB | Homo sapiens (human) | FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK |
| 2 | A | 1-[4-(6-amino-9H-purin-9-yl)phenyl]-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea | non-polymer | 481.6 | 1 | Chemie (K9Y) | |||
| 3 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A: 410 - 686 (UniProt: Q05397)
| PDB | External Database | Details |
|---|---|---|
| Gly 408 | - | EXPRESSION TAG |
| Ser 409 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31957.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 481.6 | |
| All* | Total formula weight | 32439.5 |
