4K96
Structure of Binary Complex of cGAS with Bound dsDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cyclic GMP-AMP synthase | polymer | 362 | 42512.1 | 2 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) In PDB | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
| 2 | E, G | DNA-F | polymer | 17 | 5253.5 | 2 | |||
| 3 | F, H | DNA-R | polymer | 17 | 5159.3 | 2 | |||
| 4 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | water | water | 18.0 | 722 | Chemie (HOH) |
Sequence modifications
A, B: 147 - 507 (UniProt: Q8C6L5)
| PDB | External Database | Details |
|---|---|---|
| Ser 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 105849.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 105980.6 |
