4K8X
Binary complex of 9N DNA polymerase in the replicative state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase | polymer | 775 | 89826.6 | 1 | UniProt (Q56366) Pfam (PF03104) Pfam (PF00136) | Thermococcus | |
| 2 | B (T) | DNA (5'-D(P*AP*AP*AP*GP*GP*CP*GP*CP*AP*GP*TP*TP*CP*GP*CP*G)-3') | polymer | 16 | 4948.2 | 1 | |||
| 3 | C (P) | DNA (5'-D(*CP*GP*CP*GP*AP*AP*CP*TP*GP*CP*GP*(DOC))-3') | polymer | 12 | 3632.4 | 1 | |||
| 4 | D, E, F, G, H... (A) | SULFATE ION | non-polymer | 96.1 | 11 | Chemie (SO4) | |||
| 5 | M (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | P (T) | 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium | non-polymer | 471.7 | 1 | Chemie (5CY) | |||
| 7 | Q (T) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | R, S, T (A, T, P) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 1 - 775 (UniProt: Q56366)
| PDB | External Database | Details |
|---|---|---|
| Ala 141 | Asp 141 | engineered mutation |
| Ala 143 | Glu 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 98407.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1625.9 | |
| All* | Total formula weight | 100033.0 |
