4K4Y
Coxsackievirus B3 polymerase elongation complex (r2+1_form)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I, M (A, E, I, M) | RNA-dependent RNA polymerase | polymer | 472 | 53624.2 | 4 | UniProt (Q66338) Pfam (PF00680) UniProt (by SIFTS) (Q5UEA2) | Human coxsackievirus B3 | |
| 2 | B, F, J, N (B, F, J, N) | RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3') | polymer | 24 | 7629.6 | 4 | |||
| 3 | C, G, K, O (C, G, K, O) | DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*(DOC))-3') | polymer | 15 | 4799.9 | 4 | |||
| 4 | D, H, L, P (D, H, L, P) | RNA (5'-R(*GP*GP*GP*AP*GP*AP*UP*GP*A)-3') | polymer | 9 | 2974.9 | 4 | |||
| 5 | AA, FA, Q, V (I, M, A, E) | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE | non-polymer | 451.2 | 4 | Chemie (DCT) | |||
| 6 | CA, R, X (I, A, E) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 7 | BA, DA, EA, GA, HA... (I, M, A, E) | GLYCEROL | non-polymer | 92.1 | 12 | Chemie (GOL) | |||
| 8 | JA, KA, LA, MA, NA... (A, B, C, E, F...) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A, E, I, M: 1 - 462 (UniProt: Q66338)
| PDB | External Database | Details |
|---|---|---|
| Ile 252 | Leu 1975 | variant |
| Gly 463 | - | expression tag |
| Ser 464 | - | expression tag |
| Ser 465 | - | expression tag |
| Ser 466 | - | expression tag |
| His 467 | - | expression tag |
| His 468 | - | expression tag |
| His 469 | - | expression tag |
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 276114.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3086.9 | |
| All* | Total formula weight | 279201.2 |
