4K4Y

Coxsackievirus B3 polymerase elongation complex (r2+1_form)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-dependent RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-dependent RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0039694	biological_process	viral RNA genome replication
I	0003723	molecular_function	RNA binding
I	0003968	molecular_function	RNA-dependent RNA polymerase activity
I	0006351	biological_process	DNA-templated transcription
I	0039694	biological_process	viral RNA genome replication
M	0003723	molecular_function	RNA binding
M	0003968	molecular_function	RNA-dependent RNA polymerase activity
M	0006351	biological_process	DNA-templated transcription
M	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DCT A 501

Chain	Residue
A	LYS159
B	G600
B	G601
C	DOC701
A	ARG163
A	LYS167
A	ARG174
A	TYR234
A	GLY236
A	ASP329
A	GOL505
A	HOH680

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 502

Chain	Residue
A	LYS96
A	LEU97
A	GLU98

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 503

Chain	Residue
A	MET154
A	SER179
A	ASP183
A	TYR268
A	LEU269
A	CYS291
A	SER292
A	HOH678

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	GLU7
M	LYS250
M	ASP267
M	CYS270
M	ASN271
M	HOH4247

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	ARG163
A	SER164
A	LYS167
A	DCT501

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DCT E 501

Chain	Residue
E	LYS159
E	ARG163
E	LYS167
E	ARG174
E	GLY236
E	ASP329
E	GOL502
E	HOH4269
F	G600
F	G601
G	DOC701

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL E 502

Chain	Residue
E	ARG163
E	SER164
E	LYS167
E	DCT501
E	HOH4201

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT E 503

Chain	Residue
E	LYS96
E	LEU97
E	GLU98
E	LEU138

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 504

Chain	Residue
E	MET154
E	SER179
E	ASP183
E	TYR268
E	CYS291
E	SER292

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 505

Chain	Residue
E	ALA247
E	ASP267
E	CYS270
E	ASN271
E	HOH4243
I	GLU7

---

site_id	BC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DCT I 501

Chain	Residue
I	LYS159
I	ARG163
I	LYS167
I	ARG174
I	TYR234
I	GLY236
I	ASP329
I	GOL502
J	G600
J	G601
K	DOC701

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL I 502

Chain	Residue
I	ARG163
I	SER164
I	LYS167
I	DCT501

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT I 503

Chain	Residue
I	LYS96
I	LEU97
I	GLU98

---

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL I 504

Chain	Residue
I	MET154
I	SER179
I	ASP183
I	MET187
I	TYR268
I	LEU269
I	CYS291
I	SER292

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL I 505

Chain	Residue
E	GLU7
I	PRO243
I	LYS250
I	ASP267
I	CYS270
I	ASN271
I	HOH1151

---

site_id	BC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE DCT M 501

Chain	Residue
M	ARG163
M	LYS167
M	ARG174
M	TYR234
M	GLY236
M	ASP329
M	GOL502
M	HOH4201
N	G600
N	G601
O	DOC701
O	HOH905
M	LYS159

---

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL M 502

Chain	Residue
M	ARG163
M	SER164
M	LYS167
M	DCT501

---

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL M 503

Chain	Residue
M	MET154
M	SER179
M	ASP183
M	MET187
M	LEU269
M	CYS291
M	SER292

---

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL M 504

Chain	Residue
A	LYS250
A	ASP267
A	CYS270
A	ASN271
M	GLU7

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