4K4X

Coxsackievirus B3 polymerase elongation complex (r2_form), rna

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E, I, M (A, E, I, M)	RNA-dependent RNA polymerase	polymer	472	53624.2	4	UniProt (Q66338) Pfam (PF00680) UniProt (by SIFTS) (Q5UEA2)	Human coxsackievirus B3
2	B, F, J, N (B, F, J, N)	RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3')	polymer	24	7629.6	4
3	C, G, K, O (C, G, K, O)	RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*A)-3')	polymer	14	4526.8	4
4	D, H, L, P (D, H, L, P)	RNA (5'-R(P*GP*GP*GP*AP*GP*AP*UP*GP*A)-3')	polymer	9	2974.9	4
5	Q, R, T, V (A, E, I)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	S, U, W, X (A, E, I, M)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
7	AA, BA, CA, DA, EA... (C, E, F, G, I...)	water	water		18.0	729	Chemie (HOH)

Sequence modifications

A, E, I, M: 1 - 462 (UniProt: Q66338)

PDB	External Database	Details
Ile 252	Leu 1975	variant
Gly 463	-	expression tag
Ser 464	-	expression tag
Ser 465	-	expression tag
Ser 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	275021.5
Non-Polymers*	Number of molecules	8
	Total formula weight	465.6
All*	Total formula weight	275487.1

*Water molecules are not included.