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4K4J

Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9cUAB30 and the coactivator peptide GRIP-1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Retinoic acid receptor RXR-alphapolymer23125897.01UniProt (P19793)
Pfam (PF00104)
Homo sapiens (human)Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha
2B
(B)
Nuclear receptor coactivator 2 peptidepolymer131579.91UniProt (Q15596)Homo sapiensNCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3C
(A)
(2E,4E,6Z,8E)-8-(3,4-dihydronaphthalen-1(2H)-ylidene)-3,7-dimethylocta-2,4,6-trienoic acidnon-polymer294.41Chemie (1O8)
4D, E
(A, B)
waterwater18.0115Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27476.9
Non-Polymers*Number of molecules1
Total formula weight294.4
All*Total formula weight27771.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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