4K45
Auto-inhibition and phosphorylation-induced activation of PLC-gamma isozymes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | polymer | 106 | 12438.2 | 1 | UniProt (P10686) Pfam (PF00017) | Rattus norvegicus (rat) | Phosphoinositide phospholipase C-gamma-1, Phospholipase C-gamma-1, PLC-gamma-1 |
| 2 | B (B) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, short peptide | polymer | 18 | 2116.1 | 1 | UniProt (P10686) | Rattus norvegicus | Phosphoinositide phospholipase C-gamma-1, Phospholipase C-gamma-1, PLC-gamma-1 |
| 3 | C, D (A, B) | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A: 664 - 766 (UniProt: P10686)
| PDB | External Database | Details |
|---|---|---|
| Ser 661 | - | cloning artifact |
| Gln 662 | - | cloning artifact |
| Ala 663 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14554.3 | |
| All* | Total formula weight | 14554.3 |
