4K43

Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide]

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Actin, alpha skeletal muscle	polymer	375	41862.6	2	UniProt (P68135) Pfam (PF00022)	Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits)	Alpha-actin-1
2	C, F (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D, G (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	E, H (A, B)	N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide	non-polymer		531.7	2	Chemie (1PO)
5	I, J (A, B)	water	water		18.0	81	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83725.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1997.9
All*	Total formula weight	85723.1

*Water molecules are not included.