4JVF
The Crystal structure of PDE6D in complex with the inhibitor (s)-5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 152 | 17585.1 | 1 | UniProt (O43924) Pfam (PF05351) In PDB | Homo sapiens (human) | GMP-PDE delta, Protein p17 |
| 2 | B | (2S)-2-(2-phenyl-1H-benzimidazol-1-yl)-2-(piperidin-4-yl)ethyl 1-(1-benzyl-1H-benzimidazol-2-yl)piperidine-4-carboxylate | non-polymer | 638.8 | 1 | Chemie (17X) | |||
| 3 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
B: 1 - 150 (UniProt: O43924)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17585.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 638.8 | |
| All* | Total formula weight | 18223.9 |
