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4JS1

crystal structure of human Beta-galactoside alpha-2,6-sialyltransferase 1 in complex with cytidine and phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Beta-galactoside alpha-2,6-sialyltransferase 1polymer31836821.91UniProt (P15907)
Pfam (PF00777)
Homo sapiens (human)Alpha 2,6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1
2B
(B)
beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1641.51In PDB
GlyTouCan (G36191CD)
3C
(A)
4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONEnon-polymer243.21Chemie (CTN)
4D
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5E
(A)
waterwater18.041Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight36821.9
BranchedNumber of molecules1
Total formula weight1641.5
Non-Polymers*Number of molecules2
Total formula weight338.2
All*Total formula weight38801.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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