4JR2
Human procaspase-7/caspase-7 heterodimer bound to Ac-DEVD-CMK
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Procaspase-7 | polymer | 250 | 28315.2 | 2 | UniProt (P55210) Pfam (PF00656) In PDB | Homo sapiens (human) | CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3, ICE-LAP3, Caspase-7 |
| 2 | C, D | Ac-DEVD-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | ||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A, B: 57 - 303 (UniProt: P55210)
| PDB | External Database | Details |
|---|---|---|
| Ser 54 | - | expression tag |
| Asn 55 | - | expression tag |
| Ala 56 | - | expression tag |
| Ala 198 | Asp 198 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57700.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 57771.1 |
