Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | LYS76 |
| A | GLY89 |
| A | THR90 |
| A | ASP91 |
| A | HOH546 |
| A | HOH566 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| B | ASP91 |
| B | HOH662 |
| B | LYS76 |
| B | GLY89 |
| B | THR90 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR CHAIN C OF AC-DEVD-CMK |
| Chain | Residue |
| A | ARG87 |
| A | SER143 |
| A | HIS144 |
| A | GLY145 |
| A | GLN184 |
| A | CYS186 |
| A | SER231 |
| A | TRP232 |
| A | ARG233 |
| A | PRO235 |
| A | SER275 |
| A | GLN276 |
| A | HOH630 |
| C | HOH202 |
| C | HOH203 |
| C | HOH204 |
| C | HOH205 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR CHAIN D OF AC-DEVD-CMK |
| Chain | Residue |
| B | ARG87 |
| B | SER143 |
| B | HIS144 |
| B | GLY145 |
| B | GLN184 |
| B | CYS186 |
| B | SER231 |
| B | TRP232 |
| B | ARG233 |
| B | SER234 |
| B | PRO235 |
| B | SER275 |
| B | GLN276 |
| B | HOH556 |
| D | HOH201 |
| D | HOH202 |
| D | HOH203 |
| D | HOH204 |
| D | HOH205 |
| D | HOH207 |
Functional Information from PROSITE/UniProt
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HtnaaCfaCiLLSHG |
| Chain | Residue | Details |
| A | HIS131-GLY145 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKLFFIQACRG |
| Chain | Residue | Details |
| A | LYS177-GLY188 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS144 | |
| B | HIS144 | |
| Chain | Residue | Details |
| A | CYS186 | |
| B | CYS186 | |
| Chain | Residue | Details |
| A | ARG187 | |
| A | TYR223 | |
| B | ARG187 | |
| B | TYR223 | |
| Chain | Residue | Details |
| A | THR173 | |
| B | THR173 | |
| Chain | Residue | Details |
| A | ARG233 | |
| B | ARG233 | |
| Chain | Residue | Details |
| A | SER239 | |
| B | SER239 | |
