4JNC
Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bifunctional epoxide hydrolase 2 | polymer | 315 | 36135.4 | 1 | UniProt (P34913) Pfam (PF00561) | Homo sapiens (human) | Cytosolic epoxide hydrolase 2, CEH, Epoxide hydratase, Soluble epoxide hydrolase, SEH, Lipid-phosphate phosphatase |
| 2 | B (A) | 1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[2-(trifluoromethyl)benzyl]piperidine-4-carboxamide | non-polymer | 408.4 | 1 | Chemie (1LF) | |||
| 3 | C (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 238 - 549 (UniProt: P34913)
| PDB | External Database | Details |
|---|---|---|
| Gly 237 | - | expression tag |
| Ala 550 | - | expression tag |
| Asp 551 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36135.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 408.4 | |
| All* | Total formula weight | 36543.8 |
