4JNA

Crystal structure of the DepH complex with dimethyl-FK228

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DepH	polymer	340	36751.5	2	UniProt (A4ZPY8) Pfam (PF07992) In PDB	Chromobacterium violaceum
2	H, I	Dimethyl FK228	polymer	5	588.8	2	BIRD (PRD_001184)
3	A, B	FLAVIN-ADENINE DINUCLEOTIDE	non-polymer		785.5	2	Chemie (FAD)
4	A, B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	A, B	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
7	B	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8		water	water		18.0	266	Chemie (HOH)

Sequence modifications

A, B: 22 - 340 (UniProt: A4ZPY8)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	74680.5
Non-Polymers*	Number of molecules	10
	Total formula weight	2077.3
All*	Total formula weight	76757.9

*Water molecules are not included.