4JLX
Structure of porcine cyclic GMP-AMP synthase (cGAS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Uncharacterized protein | polymer | 366 | 42472.2 | 1 | UniProt (I3LM39) Pfam (PF03281) Pfam (PF20266) | Sus scrofa (pigs swine wild boar) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, E, G (A) | MALONATE ION | non-polymer | 102.0 | 3 | Chemie (MLI) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 6 | I (A) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 135 - 497 (UniProt: I3LM39)
| PDB | External Database | Details |
|---|---|---|
| Gly 132 | - | expression tag |
| Ala 133 | - | expression tag |
| Met 134 | - | expression tag |
| Asp 268 | - | SEE REMARK 999 |
| Thr 269 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42472.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 852.1 | |
| All* | Total formula weight | 43324.3 |
