4JLF
Inhibitor resistant (R220A) substitution in the Mycobacterium tuberculosis beta-lactamase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 265 | 28186.6 | 1 | UniProt (P0C5C1) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) | Mycobacterium tuberculosis | Penicillinase |
| 2 | B, C, D, E, F (A) | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
| 3 | G (A) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
| PDB | External Database | Details |
|---|---|---|
| Ala 236 | Arg 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28186.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 474.9 | |
| All* | Total formula weight | 28661.5 |
