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4JLF

Inhibitor resistant (R220A) substitution in the Mycobacterium tuberculosis beta-lactamase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ABeta-lactamasepolymer26528186.61UniProt (P0C5C1)
Pfam (PF00144)
Pfam (PF13354)
UniProt (by SIFTS) (P9WKD3)
In PDB
Mycobacterium tuberculosisPenicillinase
2APHOSPHATE IONnon-polymer95.05Chemie (PO4)
3waterwater18.0278Chemie (HOH)
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
PDBExternal DatabaseDetails
Ala 236Arg 236engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28186.6
Non-Polymers*Number of molecules5
Total formula weight474.9
All*Total formula weight28661.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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