4JLF
Inhibitor resistant (R220A) substitution in the Mycobacterium tuberculosis beta-lactamase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-lactamase | polymer | 265 | 28186.6 | 1 | UniProt (P0C5C1) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) In PDB | Mycobacterium tuberculosis | Penicillinase |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
3 | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
PDB | External Database | Details |
---|---|---|
Ala 236 | Arg 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28186.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 474.9 | |
All* | Total formula weight | 28661.5 |