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4JKT

Crystal structure of mouse Glutaminase C, BPTES-bound form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Glutaminase kidney isoform, mitochondrialpolymer47953327.04UniProt (D3Z7P3)
Pfam (PF17959)
Pfam (PF04960)
Mus musculus (mouse)GLS
2E, F
(B, D)
N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)non-polymer524.72Chemie (04A)
3G, H, I, J
(A, B, C, D)
waterwater18.0267Chemie (HOH)
Sequence modifications
A, B, C, D: 128 - 555 (UniProt: D3Z7P3)
PDBExternal DatabaseDetails
Gly 125-expression tag
Ser 126-expression tag
His 127-expression tag
His 556-expression tag
Ser 557-expression tag
Phe 558-expression tag
Gly 559-expression tag
Pro 560-expression tag
Leu 561-expression tag
Asp 562-expression tag
Tyr 563-expression tag
Glu 564-expression tag
Ser 565-expression tag
Leu 566-expression tag
Gln 567-expression tag
Gln 568-expression tag
Glu 569-expression tag
Leu 570-expression tag
Ala 571-expression tag
Leu 572-expression tag
Lys 573-expression tag
Asp 574-expression tag
Thr 575-expression tag
Val 576-expression tag
Trp 577-expression tag
Lys 578-expression tag
Lys 579-expression tag
Val 580-expression tag
Ser 581-expression tag
Pro 582-expression tag
Glu 583-expression tag
Ser 584-expression tag
Ser 585-expression tag
Asp 586-expression tag
Asp 587-expression tag
Thr 588-expression tag
Ser 589-expression tag
Thr 590-expression tag
Thr 591-expression tag
Val 592-expression tag
Val 593-expression tag
Tyr 594-expression tag
Arg 595-expression tag
Met 596-expression tag
Glu 597-expression tag
Ser 598-expression tag
Leu 599-expression tag
Gly 600-expression tag
Glu 601-expression tag
Arg 602-expression tag
Ser 603-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight213307.8
Non-Polymers*Number of molecules2
Total formula weight1049.4
All*Total formula weight214357.2
*Water molecules are not included.

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PDB entries from 2024-10-30

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