4JKT

Crystal structure of mouse Glutaminase C, BPTES-bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004359	molecular_function	glutaminase activity
A	0006541	biological_process	glutamine metabolic process
B	0004359	molecular_function	glutaminase activity
B	0006541	biological_process	glutamine metabolic process
C	0004359	molecular_function	glutaminase activity
C	0006541	biological_process	glutamine metabolic process
D	0004359	molecular_function	glutaminase activity
D	0006541	biological_process	glutamine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 04A B 701

Chain	Residue
B	ARG322
C	LEU326
C	PHE327
C	LEU328
C	ASN329
C	TYR399
B	LYS325
B	LEU326
B	PHE327
B	LEU328
B	ASN329
B	GLU330
B	TYR399
C	LYS325

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 04A D 701

Chain	Residue
A	ARG322
A	LYS325
A	LEU326
A	PHE327
A	LEU328
A	ASN329
A	GLU330
A	TYR399
C	ARG322
D	ARG322
D	LYS325
D	PHE327
D	LEU328
D	ASN329
D	GLU330
D	TYR399

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Region: {"description":"Highly mobile activation loop","evidences":[{"source":"PubMed","id":"27542409","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22228304","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3SS5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O94925","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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