4JKI
Crystal Structure of N10-Formyltetrahydrofolate Synthetase with ZD9331, Formylphosphate, and ADP
Replaces: 3SINEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Formate--tetrahydrofolate ligase | polymer | 559 | 60012.0 | 2 | UniProt (Q2RM91) Pfam (PF01268) | Moorella thermoacetica | Formyltetrahydrofolate synthetase, FHS, FTHFS |
| 2 | C (A) | 2,7-dimethyl-6-[(prop-1-yn-1-ylamino)methyl]quinazolin-4(3H)-one | non-polymer | 241.3 | 1 | Chemie (ZD9) | |||
| 3 | D (A) | formyl phosphate | non-polymer | 126.0 | 1 | Chemie (XPO) | |||
| 4 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | F, G, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120024.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1178.7 | |
| All* | Total formula weight | 121202.7 |
