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4JIA

JAK2 kinase (JH1 domain) in complex with compound 9

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATyrosine-protein kinase JAK2polymer30035342.11UniProt (O60674)
Pfam (PF07714)
In PDB
Homo sapiens (human)Janus kinase 2, JAK-2
2A5-(4-methoxyphenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-aminenon-polymer414.51Chemie (1K3)
3AGLYCEROLnon-polymer92.11Chemie (GOL)
4waterwater18.0164Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35342.1
Non-Polymers*Number of molecules2
Total formula weight506.6
All*Total formula weight35848.7
*Water molecules are not included.

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PDB entries from 2024-07-17

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