4JI9

JAK2 kinase (JH1 domain) in complex with TG101209

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein kinase JAK2	polymer	300	35342.1	2	UniProt (O60674) Pfam (PF07714) In PDB	Homo sapiens (human)	Janus kinase 2, JAK-2
2	A, B	N-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide	non-polymer		509.7	2	Chemie (1M3)
3		water	water		18.0	110	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70684.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1019.3
All*	Total formula weight	71703.6

*Water molecules are not included.