4JGT

Structure and kinetic analysis of H2S production by human Mercaptopyruvate Sulfurtransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	3-mercaptopyruvate sulfurtransferase	polymer	299	33498.6	3	UniProt (P25325) Pfam (PF00581)	Homo sapiens (human)	MST
2	D, H, J (A, B, C)	PYRUVIC ACID	non-polymer		88.1	3	Chemie (PYR)
3	E, F, G, I, K... (A, B, C)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4	O (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5	P, Q, R (A, B, C)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

A, B, C: 11 - 289 (UniProt: P25325)

PDB	External Database	Details
Met -9	-	expression tag
Gly -8	-	expression tag
Ser -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Leu 4	-	expression tag
Val 5	-	expression tag
Pro 6	-	expression tag
Arg 7	-	expression tag
Gly 8	-	expression tag
Ser 9	-	expression tag
His 10	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	100495.9
Non-Polymers*	Number of molecules	12
	Total formula weight	1124.8
All*	Total formula weight	101620.6

*Water molecules are not included.