4JFA

Crystal Structure of Plasmodium falciparum Tryptophanyl-tRNA synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tryptophan--tRNA ligase	polymer	420	48827.5	4	UniProt (Q8IDW3) Pfam (PF00579)	Plasmodium falciparum
2	E, G, I, K (A, B, C, D)	TRYPTOPHAN	non-polymer		204.2	4	Chemie (TRP)
3	F, H, L (A, B, D)	BETA-MERCAPTOETHANOL	non-polymer		78.1	3	Chemie (BME)
4	J, M (C, D)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	N, O, P, Q (A, B, C, D)	water	water		18.0	239	Chemie (HOH)

Sequence modifications

A, B, C, D: 228 - 632 (UniProt: Q8IDW3)

PDB	External Database	Details
Met 226	-	expression tag
Ala 227	-	expression tag
Glu 633	-	expression tag
Asn 634	-	expression tag
Leu 635	-	expression tag
Tyr 636	-	expression tag
Phe 637	-	expression tag
Gln 638	-	expression tag
Gly 639	-	expression tag
His 640	-	expression tag
His 641	-	expression tag
His 642	-	expression tag
His 643	-	expression tag
His 644	-	expression tag
His 645	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	195309.9
Non-Polymers*	Number of molecules	9
	Total formula weight	1129.5
All*	Total formula weight	196439.4

*Water molecules are not included.